The UEFA Champions League always delivers high-stakes drama, and the upcoming Liverpool vs PSV Eindhoven showdown on November 26, 2025, promises to be no exception. As Liverpool aim to bounce back from a turbulent domestic season and solidify their spot in the knockout stages, PSV arrive at Anfield unbeaten in 11 games across all competitions. This Matchday 5 fixture in the league phase could be a pivotal moment for both sides. Dive into our comprehensive preview, covering match details, head-to-head history, predicted lineups, and our score prediction for this thrilling encounter.
Match Details: Liverpool vs PSV Eindhoven
Liverpool welcome PSV Eindhoven to Anfield for a crucial UEFA Champions League league phase clash on Wednesday, November 26, 2025. Kick-off is scheduled for 8:00 PM GMT (3:00 PM ET), giving fans across the globe plenty of time to tune in. The iconic Anfield Stadium, with its capacity of 61,276 and legendary atmosphere, will host the game on a grass surface. Expect cool English weather – around 46°F with light rain – which could make conditions slippery and test both teams’ adaptability.
Referee Alejandro Hernández from Spain takes charge, assisted by VAR official Guillermo Cuadra Fernandez (also Spain). This marks the second meeting between the clubs in as many seasons in the Champions League.
Current standings add intrigue: Liverpool sit eighth with nine points from four games (wins over Atlético Madrid, Eintracht Frankfurt, and Real Madrid; a loss to Galatasaray), while PSV languish in 18th with five points (a 6-2 thrashing of Napoli highlights their potential, but draws against Bayer Leverkusen and Olympiacos temper expectations). A win for the Reds strengthens their knockout push; for PSV, it’s a must to keep qualification hopes alive.
Head-to-Head History: Liverpool’s Edge at Anfield
The Liverpool vs PSV Eindhoven head-to-head record tilts firmly in the Reds’ favor, with seven previous European meetings yielding five Liverpool wins, one draw, and just one PSV victory. The Dutch side has netted only five goals across these clashes, compared to Liverpool’s 14, underscoring the Reds’ dominance.
Predicted Lineups: Slot’s Tactical Tweaks vs Bosz’s Fluid Attack
Arne Slot faces selection headaches after Liverpool’s 3-0 Premier League humbling by Nottingham Forest, with injuries sidelining Florian Wirtz (muscle), Conor Bradley, Giovanni Leoni, Jeremie Frimpong, and Stefan Bajcetic. Expect a 4-2-3-1 to harness Anfield’s energy, with Hugo Ekitiké leading the line over struggling new signing Alexander Isak, flanked by evergreen Mohamed Salah and ex-PSV star Cody Gakpo.
Liverpool Predicted XI (4-2-3-1): Alisson; Szoboszlai, Konaté, Van Dijk, Robertson; Gravenberch, Mac Allister; Salah, Jones, Gakpo; Ekitiké.
PSV boss Peter Bosz boasts near-full fitness, missing only Ruben van Bommel (knee) and Alassane Pléa. Their 4-2-3-1 thrives on quick transitions, with in-form Guus Til (seven goals in seven games) spearheading the attack and midfield maestros Joey Veerman and Ismael Saibari pulling strings.
PSV Eindhoven Predicted XI (4-2-3-1): Kovář; Dest, Schouten, Gasiorowski, Salah-Eddine; Junior, Veerman; Man, Saïbari, Perišić; Til.
Key battles? Salah vs PSV’s backline and Til exploiting Liverpool’s recent defensive lapses.
Score Prediction: Liverpool to Edge a Tense Thriller
Despite Liverpool’s domestic woes – winless in four league games and shipping goals freely – Anfield’s magic in Europe (13 straight group-stage home wins) should prevail. PSV’s leaky defense (both teams scored in their last 10 UCL games) and poor record away to English sides (one win in 14) tilt the odds. Betting markets price Liverpool at -345 favorites, with Over 2.5 Goals likely given both sides’ attacking flair.
Our Prediction: Liverpool 2-1 PSV Eindhoven.
