As the UEFA Champions League league phase heats up, FC Barcelona vs Olympiacos on October 21, 2025, promises to be a pivotal clash at the Estadi Olímpic Lluís Companys. With Barcelona aiming to climb the standings after a mixed start and Olympiacos desperate for their first win, this matchup blends Catalan flair with Greek resilience. In this comprehensive guide, we’ll dive into the head-to-head history, a detailed match preview, predicted lineups, and our score prediction.

FC Barcelona vs Olympiacos Head-to-Head

FC Barcelona and Olympiacos have locked horns just twice in competitive fixtures, both during the 2017-18 UEFA Champions League group stage. The Blaugrana hold a slight edge, with one victory, one draw, and no losses against the Greek champions. Here’s a quick breakdown:

Date Competition Result Key Scorers (Barcelona) Key Scorers (Olympiacos)
Oct 31, 2017 UCL Group Stage Olympiacos 0-0 Barcelona None None
Oct 18, 2017 UCL Group Stage Barcelona 3-1 Olympiacos Messi, Suárez, own goal Nikolaou
Barcelona’s home win in 2017 was a thriller, sparked by an early own goal from Dimitrios Nikolaou before Lionel Messi and Luis Suárez sealed the deal, despite a red card to Gerard Piqué. The return leg ended in a gritty stalemate, helping Barça top the group. Notably, Barcelona remain unbeaten in seven European home games against Greek sides, while Olympiacos have lost 14 of 16 away European matches versus Spanish teams (drawing twice). This history favors the hosts, but Olympiacos’ counter-attacking style could test a depleted Barça defence.

Match Preview

Barcelona enter this fixture in 16th place in the Champions League league phase with three points from two games—a 2-1 away win over Newcastle United followed by a frustrating 2-1 home loss to Paris Saint-Germain. Domestically, Hansi Flick’s side sit two points behind Real Madrid in La Liga after a dramatic 2-1 stoppage-time victory over Girona on October 19, thanks to Ronald Araujo’s late heroics. However, the Catalan giants are grappling with a mounting injury crisis, missing stars like Robert Lewandowski, Raphinha, Ferran Torres, Dani Olmo, Gavi, and goalkeepers Marc-André ter Stegen and Joan García. This could force rotations ahead of Saturday’s El Clásico, but young talents like Lamine Yamal—who has four goals in his last five UCL home games—offer hope.

Olympiacos, meanwhile, languish in 29th with just one point: a 0-0 home draw against Pafos FC after a 2-0 loss to Arsenal. They’re yet to score in the competition, managing only six shots on target across those outings. In the Greek Super League, José Luis Mendilibar’s men top the table after a 2-0 away win over AEL Larissa, powered by Ayoub El Kaabi’s brace. Mendilibar, who has lost 23 of 27 managerial clashes against Barcelona, will lean on a defensive setup, having conceded twice in each of their last 11 UCL away defeats.

Predicted Lineups: Injuries Shape Barcelona’s Approach

Barcelona’s injury list forces a youth-infused XI, with Wojciech Szczęsny in goal and Fermín López leading the attack. Flick may rest Pedri and Alejandro Balde for El Clásico.

FC Barcelona Predicted XI (4-3-3): Szczęsny; Koundé, Araujo, Cubarsí, Martín; De Jong, Casadó, Pedri; Yamal, Fermín, Rashford

Substitutes: Iñaki Peña (GK), Balde, Christensen (doubt), Olabisi, Gündo, Bernal, Guerra.

Olympiacos welcome back Roman Yaremchuk from injury but miss Rodinei and Gabriel Strefezza, with several players ineligible for the UCL squad.

Olympiacos Predicted XI (4-2-3-1): Tzolakis; Costinha, Retsos, Mancha, Ortega; Hezze, Scipioni; Chiquinho, Podence, El Kaabi; Yaremchuk

Substitutes: Paschalakis (GK), Biancone, Quaresma, Alexandropoulos, Milić, Fortounis, Jovetić.

El Kaabi, with seven shots but no UCL goals yet, will be key for the visitors’ counters.

FC Barcelona vs Olympiacos Score Prediction

Despite Barcelona’s absences, their home dominance and Olympiacos’ goalless UCL start tilt the scales. The Greeks’ 11-game away losing streak in the competition and inability to breach Spanish defenses suggest a controlled win for the hosts. Yamal’s flair could unlock the defense, while Mendilibar’s deep block limits damage.

Predicted Score: FC Barcelona 2-0 Olympiacos

TOPICS: FC Barcelona Olympiacos