As Serie A heats up in the 2025-26 season, all eyes are on the San Siro for a pivotal Matchday 13 showdown between AC Milan vs Lazio on November 29, 2025. With Milan chasing the top spot and Lazio aiming to climb into European contention, this fixture promises drama, tactical battles, and potential fireworks. Fresh off a gritty Derby della Madonnina victory, the Rossoneri host a resilient Biancocelesti side under Maurizio Sarri. In this comprehensive preview, we’ll dive into match details, potential lineups and score predictions to help you gear up for kickoff.
Match Details
The AC Milan vs Lazio clash is set for Saturday, November 29, 2025, with kickoff at 20:45 CET (7:45 PM GMT / 2:45 PM ET / 11:45 AM PT) at the iconic Stadio Giuseppe Meazza (San Siro) in Milan, Italy. This is Matchday 13 of the Serie A campaign, and the referee is Giuseppe Collu, with VAR handled by Di Paolo.
Predicted Lineups
Allegri sticks to his reliable 3-5-2 for balance, while Sarri deploys a fluid 4-3-3 emphasizing possession. Injuries hit both: Milan without Zachary Athekame and possibly Pulisic; Lazio missing Samuel Gigot, Matteo Cancellieri, Nicolo Rovella, and Taty Castellanos.
AC Milan Predicted XI (3-5-2)
- GK: Mike Maignan
- DEF: Fikayo Tomori, Matteo Gabbia, Strahinja Pavlovic
- MID: Alexis Saelemaekers, Youssouf Fofana, Luka Modric, Adrien Rabiot, Davide Bartesaghi
- FWD: Christopher Nkunku, Rafael Leao
Lazio Predicted XI (4-3-3)
- GK: Ivan Provedel
- DEF: Adam Marusic, Ivan Gila, Alessio Romagnoli, Luca Pellegrini
- MID: Matteo Guendouzi, Matias Vecino, Toma Basic
- FWD: Gustav Isaksen, Boulaye Dia, Mattia Zaccagni
Score Predictions
Expert consensus leans toward a Milan win, given their home form and H2H edge, but Lazio’s defensive streak (5 clean sheets in 6) suggests caution. Odds: Milan -145, Draw +300, Lazio +380; Over/Under 2.5 at 2.5 goals.
Our Prediction: AC Milan 1-0 Lazio – Pulisic or Leao nicks it late; Milan’s xG (18.8) edges Lazio’s (13.3), but under 2.5 goals hits in 6 straight for Lazio.
