United States stock futures slipped in early Tuesday trade, with the Dow Jones Industrial Average dropping over 250 points, as investors shifted focus to renewed trade frictions between the U.S. and China and awaited cues on interest rate outlook from the Federal Reserve.

At 4:03 a.m. ET, the Dow Jones declined 0.58% or 270 points, while the Nasdaq 100 slid 1.18% or 295 points, and the S&P 500 fell 0.89%.

The weakness followed escalating trade rhetoric between Washington and Beijing. While U.S. President Donald Trump insisted that trade relations would be “fine,” China announced new U.S.-related sanctions, adding to market unease.

Investors are also awaiting Federal Reserve Chair Jerome Powell’s speech later today for fresh signals on potential rate cuts amid mounting geopolitical and fiscal uncertainty.

Meanwhile, the euro traded 0.13% lower against the U.S. dollar, hovering around 1.15536 at 4:10 a.m. ET, as risk sentiment remained cautious across global markets.