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Amy Schumer, the comedian and actress known for her bold humor and candid approach to body image, has become the center of online discussion once again—this time for her noticeable weight loss. The 44-year-old star, who has long championed body positivity and openness about health struggles, surprised fans after appearing visibly slimmer in new photos from her recent Las Vegas trip. The transformation quickly fueled speculation about whether she used any external methods or medication to achieve her new look.
Amy shared photos from her girls’ trip to Las Vegas on October 4, 2025, featuring her close friends Alex Saks and Jillian Bell. In the images, the Trainwreck actress looked radiant in a chic Miu Miu button-down mini shirt dress paired with sleek black heels. Her toned legs and glowing confidence became the talk of the internet, drawing admiration from fans and celebrities alike.
Among the flood of comments, skincare expert Georgia Louise wrote, “Amy… legs need to come out more!!!” Filmmaker Lee Daniels added, “Skinnnnnnnny mommmmma,” while Real Housewives of New Jersey star Margaret Josephs praised, “Ok legs for days!!” The post quickly went viral as many applauded Amy for looking “healthy and happy.”
However, this isn’t the first time Amy has discussed her health and body transformation openly. According to People, she previously revealed that she underwent liposuction in 2022 after struggling with endometriosis and weight fluctuations. Later, she experimented with weight-loss medications, including Ozempic and Mounjaro, but her experience wasn’t positive.
During an interview on The Howard Stern Show earlier in 2025, Amy explained that while Ozempic worked well for many, it severely affected her health. She described her experience, saying, “I was bedridden. I was vomiting, and then you have no energy. Other people take it, and they’re all good. So, God bless them.”
Following her experience, Amy chose to focus on balanced health routines and emotional well-being instead of relying on medication. She has also continued to advocate for body acceptance and transparency about how difficult maintaining health can be, especially for women in the public eye.
Her latest appearance in Las Vegas not only reflected her physical transformation but also her renewed sense of confidence and vitality, reminding fans why she remains one of Hollywood’s most authentic and relatable figures.