Kyiv has neither confirmed nor denied involvement in Monday's reported drone strikes. Ukrainian officials have previously stated they will use force to hit logistical targets and supply lines inside Russia.
Russia has not officially confirmed the nuclear element of the upcoming drills. However, the mere suggestion of simulating nuclear strikes is likely to stoke fears about the potential for escalation in the year-old conflict.
Medvedev's ominous message went on to suggest that Western leaders would not be able to seek refuge in their traditional seats of power.
These tensions have reached new heights, with diplomatic channels strained and mutual mistrust running deep. The crisis in Ukraine, in particular, has been a flashpoint, with Russia's annexation of Crimea in 2014.
In response to the attacks, Ukrainian officials have condemned Russia's actions, denouncing them as flagrant violations of international law.
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